ea0063p531 | Diabetes, Obesity and Metabolism 2 | ECE2019
Jemel Manel
, Jemel Manel
, Jemaa Maroua Ben
, Kandara Hajer
, Jemni Houda
, Kammoun Ines
Introduction: Thiamine responsive megaloblastic anemia (TRMA) syndrome, also known Rogers syndrome is a rare autosomal recessive inherited disorder characterized by a triad features of megaloblastic anemia, sensorineural deafness and diabetes mellitus. TRMA manifestation is caused by mutations in the gene SLC19A2 encoding a high-affinity thiamine transporter, which disturbs the active thiamine uptake into cells.Case Presentation...